http://hdl.handle.net/123456789/20258 Sat, 04 Apr 2026 11:17:08 GMT 2026-04-04T11:17:08Z http://hdl.handle.net/123456789/20340 Early Complications of Surfactant Administration In Neonates Hafiz zulqarnain, Muhammad Tariq Nadeem; Sammar Hussain, Ali Mujtaba; Saeed Zaman, Waleed Ali Objective: To assess the early complications of surfactant administration in neonates with respiratory distress syndrome. Study Design: Perspective longitudinal study. Place and Duration of Study: Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Jun to Dec 2021. Methodology: A total of 64 neonates admitted in ICU with gestational age 27-32 weeks requiring Continuous Positive Airway Pressure and surfactant administration were included. Neonatal complications after 24 hours of administration of surfactant and final outcome was recorded on a predesigned data collection tool. Results: Mean duration of stay on ventilator was 41.12±8.88 hours. Mean duration for Continuous Positive Airway Pressure was 43.59±22.70 hours. Second dose of surfactant was given to 34(53.1%) of neonates. Among neonates 25% suffered from pulmonary hemorrhage and 7.8% from bradycardia, 48(75%) were discharged and 16(25%) died. Conclusion: The mortality rate decreased in neonates after administration of surfactant. In future, we will implement surfactant in term neonates, diagnosed with Respiratory Distress Syndrome, in order to improve the survival of neonates and reduce complications. Professor Dr Saeed Zaman Pediatrics BUCM Mon, 01 Jan 2024 00:00:00 GMT http://hdl.handle.net/123456789/20340 2024-01-01T00:00:00Z http://hdl.handle.net/123456789/20325 Evaluate the Mean Effect of Oral 25% Glucose Solution for Pain Relief in Term Infants, as Compared with Control Group, During Venipuncture Usama Rana Mehmood, Zeeshan Ahmed; Saeed Zaman Khattak, Samina Tabussam; Ayla Ahmad Jaspal Objective: To determine the efficacy of 25% oral glucose solution in providing analgesia as compared to control group in full term neonates undergoing venipuncture. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Paediatrics, Pak-Emirates Military Hospital, Rawalpindi Pakistan, from Nov 2021 to Apr 2022. Methodology: A total of 112 neonates born at full-term requiring venipuncture were included in our study. Neonates who required more than one prick per cannulation, those who couldn’t tolerate oral feeding, or had received opiates, sedatives or NSAIDs since birth were excluded. All patients underwent venipuncture, however, patients in Group A received oral 25% glucose solution while those in Group B received breast milk. All patients were scored according to the NIP score at 1-, 5- and 10-minutes post venipuncture. Data was analyzed by SPSS 26.0. Results: The patients in our sample had a mean age of 2.85±1.24 days, of whom males were 67(59.8%). The average time taken per venipuncture was 30.11±6.65 seconds. There was no difference between the two groups at baseline in terms of NIPS. In addition, no statistical difference between the two groups post-procedure in terms of NIPS was seen at 1-, 5- and 10-minutes post-venipuncture (p=0.201, p=0.411 and p=0.454, respectively). Conclusion: The use of oral 25% glucose solution can be used a comparable substitute to breast milk in the provision of anal gesia for neonates who have trouble with lactation, while undergoing venipuncture. Professor Dr Saeed Zaman Pediatrics BUCM Sun, 01 Jan 2023 00:00:00 GMT http://hdl.handle.net/123456789/20325 2023-01-01T00:00:00Z http://hdl.handle.net/123456789/20326 Validity of Shine and Lal Index {MCV2XMCHX0.01} in Predicting Iron Deficiency Anemia Sammar Hussain, Saeed Zaman; Samina Tabassum, Hafiz Zulqarnain; Atif Aziz Rana, Atif Naseem Abbasi Objective: To determine the diagnostic accuracy of the Shine and Lal index in detecting the presence of iron deficiency anae-mia, keeping serum ferritin levels and serum transferrin saturation as the gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Department of Paediatrics, Pak-Emirates Military Hospital, Rawalpindi Pakistan, Nov 2021 to May 2022. Methodology: We studied a total of 113 patients who presented with microcytic anaemia were included for study. Patients diagnosed as cases of thalassemia, haemolytic anaemia, iron deficiency anaemia, had received blood transfusions within the past three months, or were receiving iron therapy within the six months were excluded. The diagnosis of iron deficiency was based on a serum ferritin level of less than 14 ng/mL and/or a transferrin saturation of less than 20%. A Shine and Lal index greater than 1530 was considered diagnostic for iron deficiency anaemia. Results: The mean age of our sample was 6.64±2.89 years, 52.2% of whom were male. The Shine and Lal index carried a sensi-tivity of 34.8%, a specificity of 74.6% and a diagnostic accuracy of 58.4% in predicting the presence of iron deficiency anaemia, using a cut-off level greater than 1530. A total of 9.7% of patients tested positive for ß-thalassemia trait. Conclusion: The Shine and Lal index can be employed as a useful, rapid screening test performed on indices readily available as a standard part of complete blood counts but should not be used in isolation. Professor Dr Saeed Zaman Pediatrics BUCM Sun, 01 Jan 2023 00:00:00 GMT http://hdl.handle.net/123456789/20326 2023-01-01T00:00:00Z http://hdl.handle.net/123456789/20324 Calcium and Magnesium Levels in Children with Febrile Seizures Admitted in a Tertiary Care Hospital Atif Naseem Abbasi, Farooq Ikram; Saeed Zaman, Syed Hassan Nawaz; Sammar Hussain, Hassnain Shahid Objective: To determine the diagnostic accuracy of hypocalcaemia and hypomagnesaemia in paediatric patients suffering from febrile seizures. Study Design: Cross-sectional validation study. Place and Duration of Study: Department of Pediatrics, Pak-Emirates Military Hospital, Rawalpindi Pakistan, Jul 2021 to Feb 2022. Methodology: We included 87 patients between the ages of 1-6 years with ongoing febrile illness who had a history of febrile seizures. Those with a history of febrile seizures within the last month, suffered from organic brain disease or were on drugs that altered serum calcium and magnesium levels were excluded. Patients were tested for serum magnesium and calcium on admission and remained admitted throughout the febrile period for observation of the development of seizures. Results: The mean age ± standard deviation of our sample was 3.23±1.50 years, with 46(52.9%) males. The serum magnesium levels demonstrated that 46(52.9%) had hypomagnesaemia at a cut-off of 1.4 mEq/L, which had a sensitivity of 70.3%, a speci ficity of 55.0% and diagnostic accuracy of 59.8% in predicting the development of febrile seizures. Serum calcium levels at a cut-off of 8.8 mg/dL showed that 36(41.4%) had hypocalcaemia, which carried a sensitivity of 48.2%, a specificity of 61.7% and a diagnostic accuracy of 57.5%. Conclusion: Both serum magnesium and calcium levels had comparable diagnostic accuracy in predicting whether a patient with a history of febrile seizures would go on to develop febrile seizures during the current illness. However, the individual diagnostic accuracy for this prediction could have been higher. Professor Dr Saeed Zaman Pediatrics BUCM Sun, 01 Jan 2023 00:00:00 GMT http://hdl.handle.net/123456789/20324 2023-01-01T00:00:00Z