http://hdl.handle.net/123456789/19734 2026-04-04T11:19:41Z http://hdl.handle.net/123456789/18987 Effects of High-Intensity Resistance Versus Aerobic Training in PCOS Women at Risk for Psychological Trauma Huma Riaz, Mobeena Maqsood; Ayesha Afridi, Sarah Ehsan; Sadiq Jan Background: Polycystic ovarian syndrome (PCOS) is a prevalent and complex endocrine disorder that affects women of reproductive age. Its physical manifestations as the change in body image, fertility challenges, menstrual irregularities, and associated chronic health conditions increase their vulnerability to psychological trauma. Negative effects on psychological health significantly impact their quality of life. Objectives: The current study aimed to compare the effects of high-intensity resistance versus aerobic training on psychological health and quality of life in women with PCOS. Study Design: This was a single-blinded, randomized controlled trial. Methods: A randomized controlled trial was conducted from November 22 to April 23 at Riphah Rehabilitation Center, Islamabad, Pakistan. The female university students (n = 60), with an age range of 18 to 30 years, who were not part of any planned physical activity program, were not taking any medication, and were willing to par ticipate in the exercise trial, were recruited. They were randomly allocated into 2 groups: high-intensity resistance (HIRG) and high-intensity aerobic (HIAG) groups. Both groups underwent exercise interventions for a duration of 12 weeks. Clinical and psychological health and quality of life were assessed using validated measures, including the polycystic ovary syndrome questionnaire (PCOS-Q) and the 36-item Short Form Survey (SF-36). Assessments were conducted at baseline, 6th, and 12th weeks. Data analysis was done using SPSS-21. Results: The mean age of women in the HIRG (n = 30) versus the HIAG (n = 30) was 22.40 ± 2.4 years versus 20.63 ± 2.1 years. Between-group analysis revealed no significant difference (P > .05) between the groups in terms of postintervention total scores of the PCOS-Q and SF-36 quality of life. However, within-group analysis has shown statistically significant improvement (P < .01) in both outcome measures. Conclusion: It is concluded that both high-intensity modes of exercise, resistance, and aerobic training were found to be equally effective interventions for improving psychological health and quality of life in women with PCOS. Individualizing exercise programs to meet individual needs and preferences may aid in maximizing the psychological benefits of each exercise modality. Further investigation into the underlying processes and long-term impact of these therapies in this vulnerable population is required. Senior Associate Prof. Dr. Sadiq Jan Department of Gynaecology, BUCM 2024-01-01T00:00:00Z http://hdl.handle.net/123456789/18991 Measurement of Fetomaternal Outcome in Pregnant Patients with Sepsis Zill-E-Huma, Asma Jabeen; Sadiq Jan, Madiha Afzal; Uzma Aziz, Nayla Salman Sepsis during pregnancy is a severe condition associated with signi􀃯cant maternal and fetal morbidity and mortality. It necessitates early identi􀃯cation and intervention to mitigate adverse outcomes. Objective: The study was aimed to evaluate and compare feto-maternal outcomes in pregnant patients with sepsis versus those without sepsis. Methods: This comparative crosssectional study was conducted at Social Security Teaching Hospital, Lahore, from July 2023 to January 2024. A total of 240 pregnant women were included, with 120 diagnosed with sepsis and 120 without sepsis (control group). Obstetrically modi􀃯ed qSOFA and SOFA scores, were used for sepsis diagnosis. Data on vital signs, laboratory investigations, and fetal monitoring were collected and analyzed using SPSS version 24.0. Multivariate analysis was employed to adjust for potential confounders, and p-values of ≤ 0.05 were considered statistically signi􀃯cant. Results: The sepsis group exhibited signi􀃯cantly worse outcomes compared to the control group. The mean age was 27.8 ± 9.4 years, and mean Body mass index (BMI) was 25.3 ± 5.6. Maternal outcomes included 8.3 % oligohydramnios, 46.67% cesarean sections for non-reassuring fetal pro􀃯les, and 15 % preterm premature rupture of membranes. Maternal Intensive Care Unit ICU admission was necessary for 8.3% of patients, with a maternal mortality rate of 1.67%. Fetal outcomes included 5% intrauterine fetal growth restriction, 28.33% small for gestational age, 3.3% stillbirth, and 53.33% neonatal ICU admissions. Conclusions: Sepsis in pregnancy signi􀃯cantly increases the risk of adverse feto-maternal outcomes, including preterm birth, fetal distress, intrauterine growth restriction, and neonatal complications. Early detection and aggressive management are crucial to improving outcomes. Senior Associate Prof. Dr. Sadiq Jan Department of Gynaecology, BUCM 2024-01-01T00:00:00Z http://hdl.handle.net/123456789/18989 Prenatal Detectionof PlacentaAccreta:AComparisonof Doppler Ultrasound and MRI Zill-E-Huma, Rana Abid Ali; Humeera Naz, Madiha Afzal; Uzma Aziz, Sadiq Jan Placenta accreta is a severe maternal complication where the placenta abnormally attaches to the uterine wall, causing signi􀃯cant maternal and neonatal morbidity. Objectives: To compare the effectiveness of Doppler ultrasound and magnetic resonance imaging in the early detection of placenta accreta and their impact on maternal and fetal outcomes. Methods: Using purposive sampling, 150 high-risk pregnant women were screened with Colour Doppler Ultrasonography and magnetic resonance imaging. Findings were con􀃯rmed at delivery. Maternal outcomes included blood transfusion, emergency hysterectomy, intensive care unit admission, and hospital stay. Fetal outcomes included preterm birth, low birth weight, and neonatal intensive care unit, admission. Sensitivity, speci􀃯city, positive, and negative predictive values were calculated. Mc-Nemar's test compared modalities. Results: Of 150 patients, 74 had placenta accreta. Colour-Doppler ultrasonography had a sensitivity of 86.5% and speci􀃯city of 89.1%, diagnosing 64 cases. Magnetic resonance imaging showed 79.7% sensitivity and 83.3% speci􀃯city, identifying 59 cases. Colour-Doppler ultrasonography was linked to fewer emergency hysterectomies (p=0.032) and shorter intensive care unit stays (p=0.045). Preterm birth (p=0.028) and low birth weight (p=0.037) were higher in placenta accreta cases diagnosed with antepartum, though neonatal intensive care unit, admissions did not differ (p=0.451). Magnetic resonance imaging helped in inconclusive Colour-Doppler ultrasonography cases. Conclusions: It was concluded that Colour-Doppler ultrasonography is more effective than magnetic resonance imaging for early Placenta accreta detection, offering better diagnostic accuracy and improved outcomes. The 􀃯ndings highlight its value in the clinical management of high-risk pregnancies. Senior Associate Prof. Dr. Sadiq Jan Department of Gynaecology,BUCM 2024-01-01T00:00:00Z http://hdl.handle.net/123456789/18990 Umbilical Cord Coiling Index as A Marker of Perinatal Outcome Sadiq Jan, Ayesha Qamar; Muhammad Asif Javed, Seharish Zul􀃯��qar; Sara Jamil, Moizza Aziz Umbilical cord coiling patterns have a considerable effect on both pregnancy outcomes and fetal health. Objectives: To assess the postnatal umbilical coiling index and investigate its association with normal coiling, hypo-coiling, and hyper-coiling patterns about maternal and perinatal outcomes. Methods: This cross-sectional study was conducted at the Obstetrics and Gynecology Department of Pakistan Aeronautical Complex Hospital Kamra from January 2024 to June 2024. The patterns of umbilical cord coiling were analyzed in 200 Livebirths. This study utilized convenience sampling to select a sample of live births for assessing the relationship between the umbilical cord coiling index and perinatal outcomes. Data were collected on maternal factors and neonatal outcomes, including Apgar scores. Statistical analysis was conducted using SPSS version 26.0, with descriptive statistics to summarize the data and inferential tests (e.g., chi-square test, t-test, regression analysis) to evaluate associations between umbilical cord coiling patterns and perinatal outcomes. Results: The study revealed that hypo-coiled cords were linked to older maternal age (≥35 years) and higher gestational diabetes rates. Hypo-coiled infants had a low birth weight incidence of 28.6%, signi􀃯cantly lower coiling index (0.07 ± 0.02), and lower Apgar scores at one minute (6.8 ± 1.2) and 􀃯ve minutes (8.2 ± 0.9). These results suggest umbilical cord coiling patterns are crucial indicators of maternal health and neonatal outcomes, highlighting the need for careful monitoring in at-risk pregnancies. Conclusions: It was concluded that there is a correlation between neonatal outcomes and factors such as maternal age, gestational diabetes, and abnormal umbilical cord coiling patterns. Senior Associate Prof. Dr. Sadiq Jan Department of Gynaecology, BUCM 2024-01-01T00:00:00Z